Dysfonction C r brovasculaire Dans Le Syndrome de Wernicke Korsakoff
Le syndrome de Wernicke-Korsakoff est un desordre neuropsychiatrique devastateur resultant d'une carence severe en thiamine, le plus souvent retrouve chez les alcooliques chroniques, et caracterise par des hemorragies cerebrales et une neurodegenerescence severe entrainant des symptomes de demence. La structure et la fonction cerebrovasculaire dans ce desordre est severement compromise, et ce de facon precoce, et le present ouvrage demontre la presence d'alterations critiques au niveau de la barriere hemato-encephalique dans un modele animal de la pathologie. De plus, cet ouvrage demontre les mecanismes moleculaires cles responsables de ces lesions, en particulier le role central du stress oxydatif au niveau de l'endothelium vasculaire cerebral. Cet ouvrage met de l'emphase sur le role critique de la dysfonction cerebrovasculaire dans le processus de neurodegenerescence, et propose de nouvelles avenues therapeutiques visant a preserver l'integrite cerebrovasculaire et ainsi a prevenir ou a limiter les sequelles cerebrales dans le syndrome de Wernicke-Korsakoff ainsi que dans d'autres desordres neurodegeneratifs ou l'integrite cerebrovasculaire est severement compromise.
Adams and Victor s Principles of Neurology 10th Edition
The gold-standard text that has defined neurology – updated for today’s practice in full color The definitive text on the full-spectrum of neurology for decades, Adams and Victor's provides the treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Written in a clear, consistent tone, this classic resource will meet the needs of the seasoned professional or the aspiring clinician. Written from the perspective of the general neurologist, Adams and Victor's has been hailed as the most detailed, thorough, and authoritative text available on the subject. Adams and Victor's Principles of Neurology, Tenth Edition describes the various categories of neurologic disease and the main diseases that constitute each. Each subject is introduced by a detailed discussion of the symptoms and signs of disordered nervous function, their anatomic and physiologic bases, and their clinical implications. Adams and Victor's Principles of Neurology is logically divided into six parts: The Clinical Method of Neurology Cardinal Manifestations of Neurologic Disease Growth and Development of the Nervous System in the Neurology of Aging Major Categories of Neurologic Disease Diseases of the Spinal Cord, Peripheral Nerve, and Muscle Psychiatric Disorders The Tenth Edition is highlighted by the welcome addition of full-color photographs, expanded coverage of important subspecialties, and an increased number of tables and figures. Edition after edition, Adams and Victor's has stayed true to its original mission: to provide a well-written, readable text emphasizing a disciplined presentation of clinical data and lucid descriptions of underlying disease processes.
ICPC 2 R
This fully revised and corrected edition of the International Classification of Primary Care 2e (ICPC-2) is indispensable for anyone wishing to use the international classification system for classificaton of morbidity data in a primary care setting. The concept of ICPC-2 has not been changed but the main body of the actual classification (chapter 10) has been completely revised to reflect the adequate use for an individual patient record and for research purposes. This now brings the printed version of ICPC-2 completely in-line with the electronic version previously only available through the Oxford Website for the journal Family Practice. ICPC-2 is patient-oriented rather than disease or provider-oriented. It encompasses both the patient's reason for encounter and the patient's problem. ICPC-2 is extensively used internationally and includes a detailed conversion system for linking the ICPC and ICD-10 codes published by WHO, additional inclusion criteria, and cross-referencing rubrics. ICPC-2 It has been developed based on the recognition that building the appropriate primary care systems to allow the assessment and implementation of health care priorities is possible only if the right information is available to health care planners.
The Ghost Riders of Ordebec
‘People will die,’ says the panic-stricken woman outside police headquarters. She refuses to speak to anyone besides Commissaire Adamsberg. Her daughter has seen a vision: ghostly horsemen who target the most nefarious characters in Normandy. Since the middle ages there have been stories of murderers, rapists, those with serious crimes on their conscience, meeting a grisly end following a visitation by the riders. Soon after the young woman’s vision a notoriously vicious and cruel man disappears. Although the case is far outside his jurisdiction, Adamsberg agrees to investigate the strange happenings in a village terrorised by wild rumours and ancient feuds.
Essence of Anesthesia Practice
Essence of Anesthesiology Practice makes it easy to formulate anesthesia plans through a consistent format and discussions of the problems, causes, comorbidities, and anesthesia implications for over 600 clinical topics. Drs. Fleisher and Roizen present a completely revised new edition that includes coverage of many new conditions, procedures, and drugs. Easily formulate anesthesia plans through a consistent format that covers a single clinical topic on each page, with a review of its problems, causes, comorbidities, and anesthesia implications. Get state-of-art, reliable coverage from an international team of experts who discuss common and rare conditions and how to manage them. Understand the interactions of common drugs and alternative medicine so that you can develop anesthesia plans accordingly. Quickly reference key information using the carefully templated text that highlights the most important anesthetic considerations in a consistent, user-friendly layout. Stay current on the latest anesthetic implications in regards to coexisting diseases, procedures, drugs, and alternative and complementary therapies, including coverage of mitochondrial myopathy, atrial fibrillation ablation, awake craniotomy, stereotactic neurosurgery, neuroprotection, dexmedetomidine, and other hot topics.
The Man Who Mistook His Wife for a Hat
With an introduction by Will Self A classic work of psychology, this international bestseller provides a groundbreaking insight into the human mind. If a man has lost a leg or an eye, he knows he has lost a leg or an eye; but if he has lost a self - himself - he cannot know it, because he is no longer there to know it. In this extraordinary book, Dr. Oliver Sacks recounts the stories of patients struggling to adapt to often bizarre worlds of neurological disorder. Here are people who can no longer recognize everyday objects or those they love; who are stricken with violent tics or shout involuntary obscenities; who have been dismissed as autistic or retarded, yet are gifted with uncanny artistic or mathematical talents. If inconceivably strange, these brilliant tales illuminate what it means to be human. A provocative exploration of the mysteries of the human mind, The Man Who Mistook His Wife for a Hat is a million-copy bestseller by the twentieth century's greatest neurologist.
The Seven Sins of Memory
A groundbreaking work by one of the world's foremost memory experts, THE SEVEN SINS OF MEMORY offers the first framework that explains common memory vices -- and their surprising virtues. In this intriguing study, Daniel L. Schacter explores the memory miscues that occur in everyday life: absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence. Schacter illustrates these concepts with vivid examples -- case studies, literary excerpts, experimental evidence, and accounts of highly visible news events such as the O.J. Simpson verdict, Bill Clinton's grand jury testimony, and the search for the Oklahoma City bomber. He also delves into striking new scientific research, giving us a glimpse of the fascinating neurology of memory. Together, the stories and the scientific results provide a new look at our brains and at what we more generally think of as our minds. Winner of the William James Book Award
How the Mind Forgets and Remembers
A groundbreaking work by one of the world’s foremost memory experts that offers the first framework to explain the basic memory miscues that we all encounter. Daniel L. Schacter, chairman of Harvard University’s Psychology Department, is internationally recognised as one of the world’s authorities on memory, explains that just as the seven deadly sins, the seven memory sins appear routinely in everyday life, and why it is a good thing that they happen and surprisingly vital to a keen mind. The author explains how transience reflects a weakening of memory over time, how absent-mindedness occurs when failures of attention sabotage memory and how blocking happens when we can’t retrieve a name we know well. Three other sins involve distorted memories: misattribution (assigning a memory to the wrong source), suggestibility (implanting false memories), and bias (rewriting the past based on present beliefs). The seventh sin, persistence, concerns intrusive recollections that we cannot forget – even when we wish we could. Daniel Schacter illustrates decades of research into memory lapses with compelling, and often bizarre, examples – for example, the violinist who placed a priceless Stradivarius on top of his car before driving off and the national memory champion who was plagued by absentmindedness. This book also explores recent research, such as the imaging of the brain that actually shows memories being formed. Together the stories and scientific findings examined in How The Mind Forgets and Remembers will reassure everyone from twenty-somethings who find their lives too busy to those in their fifties and sixties who are worried about early Alzheimers. Beautifully written, this original book provides a fascinating new look at our brains and what we more generally think of as our minds.
Principles of Psychopharmacology for Mental Health Professionals
Principles of Psychopharmacology for Mental Health Professionals addresses the current "split" model of mental health care, in which physicians provide pharmaco-therapy while non-prescribing practitioners oversee other services such as psychotherapy. Bringing these two areas together, this book familiarizes mental health professionals with the medications used to treat psychiatric disorders. Prepared by world-renowned psychopharmacologists and psychiatrists, this useful resource helps non-prescribing practitioners understand when and why a given medication is appropriate to use, when it is not indicated, and what potential side effects may occur. Also discussed are the appropriate times in therapy when a referral for a medication evaluation is indicated as well as how to broach this issue with the patient. Recognizing that there are almost always a number of medications from which to choose, the authors combine research outcomes with their extensive clinical experience to highlight the important considerations in selecting one medication over another. As an educational tool, the text encourages and supports clinicians who wish to increase patients' understanding of treatment. After an introduction and overview, chapters cover: * Basics of psychopharmacology * Attention-deficit hyperactivity disorder * Mood disorders * Sleep disorders * Schizophrenia * Cognitive disorders * Anxiety disorders * Personality disorders * Substance use disorders * Traumatic brain injury * Eating disorders * Side effects Every chapter includes diagnostic considerations, history of medication treatments, and emerging trends for each disease. Principles of Psychopharmacology for Mental Health Professionals lays out what psychotherapists and other mental health practitioners need to know about psychotropic medications, giving them and their patients an invaluable guide to the full array of treatments available.
The Man Who Mistook His Wife For A Hat And Other Clinical Tales
THE MAN WHO MISTOOK HIS WIFE FOR A HAT brings together twenty-four of Oliver Sacks’ most fascinating and beloved case studies. The patients in these pages are confronted with almost inconceivably strange neurological disorders; in Sacks’ telling, their stories are a profound testament to the adaptability of the human brain and the resilience of the human spirit. Dr. Sacks treats each of his subjects—the amnesic fifty-year-old man who believes himself to be a young sailor in the Navy, the “disembodied” woman whose limbs have become alien to her, and of course the famous man who mistook his wife for a hat—with a deep respect for the unique individual living beneath the disorder. These tales inspire awe and empathy, allowing the reader to enter the uncanny worlds of those with autism, Alzheimer's, Tourette's syndrome, and other unfathomable neurological conditions. “One of the great clinical writers of the 20th century” (The New York Times), Dr. Sacks brings to vivid life some of the most fundamental questions about identity and the human mind.